International Gold Number (IGN)
The International Gold Number (IGN) is a measure of the stability of a colloidal gold solution. It is defined as the number of milligrams of potassium cyanide required to cause a color change from red to blue in 10 mL of a colloidal gold solution.
The IGN is an important factor in the stability of colloidal gold solutions. A high IGN indicates that the solution is more stable and less likely to coagulate or flocculate. This is important for applications where the stability of the colloidal gold solution is critical, such as in the preparation of gold nanoparticles for drug delivery or in the development of gold-based sensors.
The IGN can be affected by a number of factors, including the concentration of gold in the solution, the size and shape of the gold particles, and the presence of other ions in the solution. The IGN typically increases with increasing gold concentration and decreasing particle size. The presence of other ions can also affect the IGN, with some ions, such as chloride ions, having a stabilizing effect, while others, such as sulfate ions, having a destabilizing effect.
The IGN can be measured using a variety of methods, including spectrophotometry and turbidimetry. Spectrophotometry is the most common method, and it involves measuring the absorbance of the colloidal gold solution at a wavelength of 520 nm. The absorbance is then used to calculate the IGN.
The IGN is a useful tool for characterizing the stability of colloidal gold solutions. It can be used to compare the stability of different solutions, to optimize the conditions for the preparation of colloidal gold solutions, and to understand the factors that affect the stability of colloidal gold solutions.
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