International Gold Nanoparticles Definition
Gold nanoparticles (AuNPs) are defined as small spherical particles of elemental gold (Au) with diameters ranging from 1 to 100 nanometers (nm). They exhibit unique optical, electronic, and catalytic properties due to their size and shape.
The International Organization for Standardization (ISO) has established a definition for gold nanoparticles in ISO/TS 80004-4:2019 as:
> “Spherical gold nanoparticles are defined as having a three-dimensional structure with a major axis diameter of less than or equal to 100 nm and consisting of 99% or more gold by weight.”
This definition emphasizes the following key characteristics:
* Spherical Shape: The nanoparticles should have a spherical morphology.
* Size: The diameter of the nanoparticles should be below or equal to 100 nm.
* Elemental Composition: The nanoparticles should consist of predominantly gold (Au), with a purity of 99% or higher by weight.
Significance of the Definition
An internationally agreed-upon definition for gold nanoparticles is crucial for:
* Facilitating international trade and communication
* Establishing common ground for research and development
* Ensuring product quality and safety
* Providing a basis for regulatory purposes
The ISO definition serves as a reference point for scientists, manufacturers, and regulators involved in the field of gold nanoparticles. It ensures that all parties are working with a consistent understanding of what constitutes a gold nanoparticle.
Variations in Definition
It’s worth noting that other organizations may have slightly different definitions for gold nanoparticles. For example, the United States Food and Drug Administration (FDA) defines gold nanoparticles as “spheres or approximate spheres of gold” with diameters less than 50 nm.
Despite these minor variations, the ISO definition remains the most widely accepted and comprehensive definition for gold nanoparticles in the international scientific community.
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